Isla Grande Vacations from $712

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Isla Grande Vacation

With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.

The Latest Isla Grande vacation packages

Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Price was $1,037, price is now $712 per person
$712
per person
Dec 12 - Dec 19
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.4/10 Very Good! (1,006 reviews)
Beautiful hotel with amazing surroundings but the restaurant is very limited and expensive and not good 😌

Reviewed on Sep 28, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,398, price is now $1,298 per person
$1,298
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (997 reviews)
Very beautiful hotel with helpful staff. Very good dining options.

Reviewed on Sep 29, 2025

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,219, price is now $808 per person
$808
per person
Dec 5 - Dec 12
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,277 reviews)
10 out of 10 experience. Was a surprise birthday trip for my wife. She loved it and wanted to know when can we revisit.

Reviewed on Sep 30, 2025

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Bella Vista
Save 100% on your flight
Price was $1,699, price is now $1,160 per person
$1,160
per person
Dec 19 - Dec 26
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,004 reviews)
Excelent atention to detail, recomended stay.

Reviewed on Sep 20, 2025

MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 out of 5
Bella Vista
Price was $1,276, price is now $891 per person
$891
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (295 reviews)
Great place and stay

Reviewed on Sep 6, 2025

Don't see what you're looking for?
See all available trips from Columbus to Isla Grande
View all trips

Isla Grande Hotel Deals

Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira, Isla Grande, Provincia de Colón
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $92 total per night from Oct 1 to Oct 2
$92 total
Oct 1 - Oct 2
Total with taxes and fees
10/10 Exceptional! (2 reviews)
"It was old, quaint interesting, would recommend"

Reviewed on Sep 5, 2025

Hotel Cocotal
Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande, Isla Grande, Colon
10/10 Exceptional! (3 reviews)
"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."

Reviewed on Sep 5, 2025

Get rates
Ordovician Beach Resort
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01, Isla Grande, Colón Province
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $113 total per night from Oct 1 to Oct 2
$113 total
Oct 1 - Oct 2
Total with taxes and fees
6/10 (1 review)
"Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ..."

Reviewed on Sep 19, 2025

HOTEL ISLA GRANDE
See all 59 properties in Isla Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does an Isla Grande vacation package cost?
You'll find cheap prices from $712 on Expedia for your Isla Grande getaway. However, factors like the season, choice of hotel and length of stay will influence how much your vacation to Isla Grande costs.
What are the cheapest months to go to Isla Grande?
August, November and December are great times to search for cheap Isla Grande vacation packages. Opting to travel in quieter months means you can generally find lower prices on accommodations and flights.
How many days is enough for Isla Grande?
Generally, a handful of days is enough to check out the major attractions during your Isla Grande vacation. But if you prefer to have time to relax or go on day tours, think about extending your itinerary.
How to find the best Isla Grande package deals?
Bagging a cheap Isla Grande package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and browse what's available. You can customize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Isla Grande package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book an Isla Grande vacation as a package?
You can enjoy significant savings on your Isla Grande getaway by booking a personalized vacation package. Check the "Package" heading, then select your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Isla Grande?
Secure incredible bargains by booking your flights in advance with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Isla Grande break.
How to plan a trip to Isla Grande?

  1. Pick your dates: What you'd like to do in Isla Grande and your preferred season will help you decide when to get away.
  2. Set a budget: Consider expenses such as transportation, flights and meals when calculating how much to save for your trip to Isla Grande. Then, select a hotel that fits your budget, whether that's a wallet-friendly option or a lavish getaway.
  3. Use Expedia's trip planning tool to discover Isla Grande: Research every part of your trip to Isla Grande with this handy planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Decide how long to go away for: Now that you know more about Isla Grande, you can work out the ideal length of your vacation. Put together a draft itinerary and give yourself enough time to cover everything you want to see.
  5. Bundle your airfare and accommodations: Once you've settled on your dates and duration, book the perfect Isla Grande vacation package for you.
  6. Book any day trips or activities: Now to the fun part — organizing everything you want to do and see. Explore some of the exciting things to do in Isla Grande and reserve your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Isla Grande vacation packages?
Your Isla Grande break should be a relaxing escape from your busy life, not a reason for money-related stress. So to give you more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.