Isla Grande Vacations from $656

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Your Isla Grande Vacation

With a Isla Grande vacation package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande vacation is just a few clicks away with Expedia.

The Latest Isla Grande vacation packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $1,169, price is now $656 per person
$656
per person
Dec 26 - Dec 31
found 20 hours ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
20/10 Exceptional! (1 review)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,543, price is now $1,290 per person
$1,290
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
18/10 Exceptional! (1,002 reviews)
Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city.

Reviewed on Nov 16, 2025

Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
Price was $1,747, price is now $1,102 per person
$1,102
per person
Feb 1 - Feb 7
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
17.6/10 Exceptional! (149 reviews)
Loved this property, and will definitely return!

Reviewed on Aug 14, 2025

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,339, price is now $870 per person
$870
per person
Feb 4 - Feb 10
found 21 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
17.6/10 Exceptional! (3 reviews)
Reseña sugerida: La propiedad está muy bonita y completamente remodelada, lo cual se agradece mucho. Sin embargo, hubo varios detalles que no permitieron que mi estadía fuera 100% cómoda. • En los baños salía un olor desagradable de las cañerías, lo que impregnaba el ambiente. • Las baterías del control de aire acondicionado de un cuarto estaban agotadas y tuve que usar el control de otro. • La pared de piedra junto a la cama desprende un polvo fino que cae sobre la cama. • Para una estadía de 9 días, la cantidad de toallas (2), papel higiénico y bolsas de basura proporcionadas fue muy limitada. • La secadora no funcionaba, por lo que tuve que secar la ropa en otra parte de la casa. • Debido a la ubicación, se escucha bastante ruido en el apartamento. En general, la propiedad tiene mucho potencial y está bien ubicada, pero considero importante que se atiendan estos detalles para que la experiencia sea más placentera.

Reviewed on Sep 8, 2025

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,235, price is now $806 per person
$806
per person
Jan 30 - Feb 6
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
18/10 Exceptional! (4,515 reviews)
The glass between the toliot and the wash basin was dirty the whole duration of our stay. Also the bathroom door. Attention to detail is very important

Reviewed on Nov 20, 2025

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Isla Grande Hotel Deals

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
10/10 Exceptional! (3 reviews)
Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special.

Reviewed on Sep 5, 2025

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Ordovician Beach Resort
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $115 total per night from Nov 21 to Nov 22
$115 total
Nov 21 - Nov 22
Total with taxes and fees
4.6/10 (3 reviews)
Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ...

Reviewed on Sep 19, 2025

HOTEL ISLA GRANDE
Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira Isla Grande Provincia de Colón
$79 nightly
The price is $88 total per night from Nov 24 to Nov 25
$88 total
Nov 24 - Nov 25
Total with taxes and fees
10/10 Exceptional! (2 reviews)
It was old, quaint interesting, would recommend

Reviewed on Sep 5, 2025

Hotel Cocotal
See all 55 properties in Isla Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isla Grande Vacation Packages

Isla Grande Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
80ºF
Max Temp Summer
85ºF
Top Sights
Blanca Beach, Portobelo National Park and Mirador Perú

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Frequently asked questions

How much does an Isla Grande vacation package cost?
You'll find cheap prices from $656 on Expedia for your Isla Grande getaway. However, factors like the season, choice of hotel and length of stay will influence how much your vacation to Isla Grande costs.
What are the cheapest months to go to Isla Grande?
August, November and December are great times to search for cheap Isla Grande vacation packages. Opting to travel in quieter months means you can generally find lower prices on accommodations and flights.
How many days is enough for Isla Grande?
Generally, a handful of days is enough to check out the major attractions during your Isla Grande vacation. But if you prefer to have time to relax or go on day tours, think about extending your itinerary.
How to find the best Isla Grande package deals?
Bagging a cheap Isla Grande package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and browse what's available. You can customize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Isla Grande package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book an Isla Grande vacation as a package?
You can enjoy significant savings on your Isla Grande getaway by booking a personalized vacation package. Check the "Package" heading, then select your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Isla Grande?
Secure incredible bargains by booking your flights in advance with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Isla Grande break.
How to plan a trip to Isla Grande?

  1. Pick your dates: What you'd like to do in Isla Grande and your preferred season will help you decide when to get away.
  2. Set a budget: Consider expenses such as transportation, flights and meals when calculating how much to save for your trip to Isla Grande. Then, select a hotel that fits your budget, whether that's a wallet-friendly option or a lavish getaway.
  3. Use Expedia's trip planning tool to discover Isla Grande: Research every part of your trip to Isla Grande with this handy planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Decide how long to go away for: Now that you know more about Isla Grande, you can work out the ideal length of your vacation. Put together a draft itinerary and give yourself enough time to cover everything you want to see.
  5. Bundle your airfare and accommodations: Once you've settled on your dates and duration, book the perfect Isla Grande vacation package for you.
  6. Book any day trips or activities: Now to the fun part — organizing everything you want to do and see. Explore some of the exciting things to do in Isla Grande and reserve your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Isla Grande vacation packages?
Your Isla Grande break should be a relaxing escape from your busy life, not a reason for money-related stress. So to give you more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.